Impacting dementia and cognitive loss with innovative strategies: mechanistic target of rapamycin, c

• 作 者: Kenneth Maiese
• 机 构: Cellular and Molecular Signaling, Newark, NJ, USA
• 出 处: 中国神经再生研究（英文版）
• 发表日期: 2019年5期

A significant global impact from dementia: According to the World Health Organization (Dua et al., 2017), the current numbers for the prev-alence and treatment costs for dementia worldwide are staggering. Almost 50 million individuals suffer from dementia. Dementia is now considered to be the 7th leading cause of death. Currently, at least five percent of the world’s elderly population, equal to approximately 47 million individuals, have dementia. Moreover, at least sixty percent reside in low and middle income countries. Almost seventy-five percent of these new cases are to oc-cur in these countries. The number of new cases each year throughout the globe is increasing at approximately 10 million per year. By the year 2030, 82 million people are expected to have dementia and by the year 2050, 152 million are expected to have the disease.