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抗肝肾微粒体抗体(Anti-LKM)有三种,均与肝炎有关。Anti-LKM_1是Ⅰ型自身免疫性肝炎的血清标记;Anti-LKM_2可能参与氯噻苯氧酸(ticryna-fan)所致药物性肝炎的发病;Anti-LKM_3则见于慢性丁型肝炎。Anti-LKM_1相关性肝炎由于常伴器官特异性免疫紊乱(如突眼性甲状腺肿、
There are three anti-liver and kidney microsomal antibodies (Anti-LKM), all related to hepatitis. Anti-LKM_1 is a serological marker of autoimmune hepatitis type Ⅰ; Anti-LKM_2 may be involved in the pathogenesis of drug-induced hepatitis induced by ticryn-3-acetic acid; Anti-LKM_3 is found in chronic hepatitis. Anti-LKM_1-associated hepatitis is often accompanied by organ-specific immune disorders (such as exophthalmos,