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目的:研究影响甲状腺功能亢进症(甲亢)患者药物治疗预后的因素。方法:192例初诊甲亢患者用抗甲亢药物治疗1.5 a,测定血清总碘含量、血清促甲状腺激素受体抗体(TRab)浓度。多因素条件logistic回归分析各危险因素。结果:随访1.5 a 114例缓解,78例复发,对相应因素进行分析。结论:甲亢患者TRab水平高、Graves病阳性家族史、血清总碘含量高、发病年龄早可能是导致ATD治疗复发的危险因素。
Objective: To study the factors influencing the prognosis of drug therapy in patients with hyperthyroidism (hyperthyroidism). Methods: A total of 192 patients with newly diagnosed hyperthyroidism were treated with antithyroid drugs for 1.5 years. The total serum iodine and the concentration of serum thyrotropin receptor antibody (TRab) were measured. Multivariate conditional logistic regression analysis of risk factors. Results: Followed up 1.5 a 114 cases of remission, 78 cases of recurrence, the corresponding factors were analyzed. CONCLUSIONS: The high TRab level, Graves’ disease-positive family history, high serum total iodine content and early onset of disease may be the risk factors of ATD recurrence.