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目的:探讨成人腹膜后神经母细胞瘤的临床特点及治疗方式。方法:回顾性分析我院于2009年9月收治的1例成人腹膜后神经母细胞瘤的相关临床资料。结果:该患者为体检时发现,无明显临床症状,实验室检查无异常。肿瘤位于右侧肾上腺区,大小约7cm×8cm×6cm,血供丰富,与肾上腺粘连紧密。术后病理提示神经母细胞瘤,肿瘤组织侵及肾上腺包膜,未侵及肾上腺实质。免疫组织化学syn+++,CgA+++,NSE++,CD56+++。患者术后多次复发,均及时行手术切除,并辅助放化疗。随访至今,患者仍存活且未发现新发转移灶。结论:成人腹膜后神经母细胞瘤较为少见,临床症状无特殊,术后易复发,治疗关键在于及时行手术切除并辅助放化疗的综合治疗方式。患者术后应长期密切随访。
Objective: To investigate the clinical characteristics and treatment of adult retroperitoneal neuroblastoma. Methods: A retrospective analysis of our hospital in September 2009 admitted to a case of adult retroperitoneal neuroblastoma related clinical data. Results: The patient was found during physical examination, no obvious clinical symptoms, laboratory tests were normal. The tumor is located in the right adrenal area, the size of about 7cm × 8cm × 6cm, rich in blood supply, and adrenal adhesions close. Postoperative pathology prompted neuroblastoma, tumor invasion and adrenal envelope, did not invade adrenal parenchyma. Immunohistochemistry syn +++, CgA +++, NSE ++, CD56 +++. Many patients relapse after surgery, were timely surgical resection, and assisted radiotherapy and chemotherapy. Until now, the patient survived and no new metastases were found. Conclusion: The adult retroperitoneal neuroblastoma is rare, the clinical symptoms are no special, easy to relapse after surgery, the key lies in the timely treatment of surgical resection and assisted radiotherapy and chemotherapy comprehensive treatment. Patients should follow up long-term follow-up.