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目的：探讨分别采取足内侧穿支游离皮瓣和足内侧穿支带蒂皮瓣的方法对前足区域皮肤缺损进行修复的临床治疗效果。方法：选取2015年1月至2016年1月我院收治的前足皮肤缺损的患者34例，随机分成两组，每组17例，对照组采用足内侧穿支游离皮瓣的方式修复患者的前足皮肤缺损，观察组采用足内侧穿支带蒂皮瓣的方法修复患者的前足皮肤缺损，观察两组治疗效果。结果：观察组术后皮瓣淤血坏死情况及皮瓣愈合情况明显优于对照组，观察组治疗后皮瓣感觉恢复情况明显优于对照组，P<0.05，有统计学意义。结论：对前足皮肤缺损患者采取足内侧穿支带蒂皮瓣的方法进行修复，能够提高治愈效果，作用安全有效，值得临床推广应用。“,”[Abstarct]Objective:To explore the clinical experience of repairing forefoot skin defects with medial pedis perforator free flap and medial pedis perforator pedicle flap. Method: From Jan 2015 to Jan 2016, 34 cases of patients of forefoot skin defects were divided randomly into two groups, 17 cases in each group, the control group were treated by using medial pedis perforator free flap, the trial group were treated by using medial pedis perforator pedicle flap,observed treatment effects of two groups. Result:Postoperative congestion necrosis and union of the flap in the trial group was better than the control group. The recovery of flap feeling in the trial group was better than the control group.There was statistical significance(P<0.05). Conclusion:Repairing forefoot skin defects with medial pedis perforator pedicle flap can improve the effect of cure, and its clinical effect is safe and reliable.