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疑为急性心肌梗塞(AMI)患者352例,入选标准:年龄<75岁,胸痛持续时间>15min 和评估时<165min。不需心电图(ECG)标准。以双盲形式,病人随机分为接受组织型纤溶酶原激活剂(rtPA)100mg 治疗组177例和安慰剂组175例。灌注开始前静注肝素5 000IU。试验灌注完成后,开始灌注肝素,并口服抗凝剂治疗。达到双香豆素治疗血浆浓度对,停输肝素。口服抗凝剂治疗维持30天。完成试验
A total of 352 patients with suspected acute myocardial infarction (AMI) were enrolled and were enrolled: age <75 years, duration of chest pain> 15 minutes and assessment <165 minutes. No ECG standard required. In a double-blind fashion, patients were randomized to receive 177 mg of tissue plasminogen activator (rtPA) 100 mg and 175 to placebo. Heparin 5 000 IU intravenously before perfusion. After completion of the perfusion test, perfusion of heparin was started and oral anticoagulant therapy was administered. To double-coumarin plasma concentration, stop heparin. Oral anticoagulant therapy for 30 days. Complete the test