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目的 探讨局部晚期食管癌同步放化疗疗效观察。方法 42例局部晚期食管癌分为对照组和治疗组。21例对照组行单纯放疗:放化疗组21例,同时采用DF化疗方案。结果对照组近期有效率为72%,治疗组为89%。骨髓抑制方面,两组I度、Ⅱ度、Ⅲ度、Ⅳ度发生率分别为12.5%、18.8%、16.4%、0%和36.3%、27.8%、16.5%、2.1%。l、2、3年生存率分别为59.4%、35.5%、16.2%和81.5%、56.5%、18.4%。结论局部晚期食道癌同步放化疗是有效的治疗手段。
Objective To investigate the efficacy of concurrent chemoradiotherapy in locally advanced esophageal cancer. Methods 42 cases of locally advanced esophageal cancer were divided into control group and treatment group. 21 cases of control group were treated with radiotherapy alone: radiotherapy and chemotherapy group of 21 cases, while using DF chemotherapy. Results The effective rate of the control group was 72% and the treatment group was 89%. In myelosuppression, the incidence rates of I degree, II degree, III degree and IV degree were 12.5%, 18.8%, 16.4%, 0% and 36.3%, 27.8%, 16.5% and 2.1% respectively. l, 2, 3-year survival rates were 59.4%, 35.5%, 16.2% and 81.5%, 56.5% and 18.4% respectively. Conclusions Chemotherapy concurrent chemoradiotherapy in locally advanced esophageal cancer is an effective treatment.