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The fabrication of high performance CuO based glucose sensors remains a great challenge due to the“trade-off effect”between sensitivity and linear range.In this study,a hierarchical CuO nanostructure with a great number of firecracker-shaped nanorods along the ligament and three-dimensional interconnected nanoporous is obtained by dealloying and post oxidation process of Al-33.3 wt%Cu eutectic alloy ribbons.Because of the precise structural design,not only the number of active sites for glucose electro-oxidation is significantly increased but also the glucose diffusion under high concentration is greatly accelerated,leading to a high sensitivity of 1.18 mA cm-2 mM-1 and a wider linear range up to 5.53 mM for glucose detection.This work provides a potential approach to design hierarchical nanostructure for other metal oxides with desirable properties for electrocatalytic applications.