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背景全球约有20亿人或全球三分之一人曾感染乙型肝炎病毒(HBV),3.5～4亿人为慢性HBV感染。目前美国HBV感染者为125～200万。慢性HBV感染的长期危险性是肝硬化和肝细胞癌(HCC),其在围生期和生命早期感染者中的发生率为15%～30%,可能导致肝移植或英年早逝。进展为肝硬化的已知危?
Background About 2 billion people worldwide or one third of the world’s people have been infected with hepatitis B virus (HBV), and 350 to 400 million people have chronic HBV infection. At present, HBV infection in the United States is between 125 and 2 million. The long-term risk of chronic HBV infection is cirrhosis and hepatocellular carcinoma (HCC), which occurs in 15% to 30% of patients with perinatal and early-life infections and may result in liver transplantation or premature death. Progress for the known risk of cirrhosis?