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无环鸟苷是一种有效而特异的抗单疱病毒药物,能有选择地作用于单疱病毒感染的细胞。治疗树枝状角膜溃疡疗效等于或优于碘苷和阿糖腺苷,与三氟胸腺嘧啶核苷疗效相等。已证明无环鸟苷无明显的副作用,可以取代任一其它抗病毒药。局部用无环鸟苷治疗单疱病毒性树枝状角膜溃疡疗效已肯定。然而,有些患者不愿意局部用药,或因病、年老或工作关系不便于局部用药,所以安全有效易接受和采用的口服用药,对他们定会有益。另外,全身用抗病毒药可以对眼深部组织产生作用,可用于治疗诸如实质性角膜炎或
Acyclovir is a potent and specific anti-herpes simplex virus drug that selectively acts on herpes simplex virus-infected cells. Treatment of dendritic corneal ulcer efficacy equal to or better than iodine and vidarabine, and thymidine efficacy equal. Acyclovir has been shown to have no apparent side effects and can replace any of the other antiviral drugs. Topical acyclovir treatment of herpes simplex dendritic keratopathy efficacy has been affirmed. However, some patients are reluctant to use drugs locally or are not easily given topical solutions because of sickness, old age or working relationship. Therefore, safe and effective oral medication will be beneficial to them. In addition, systemic anti-viral drugs can have deep eye tissue effects, can be used to treat such as keratitis or