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背景和目的 胎儿或新生儿颅内出血(ICH)是一种胎儿或 者新生儿同种免疫性血小板减少(FNAIT)的严重并发症。为了获得预防ICH的决策,在连续血小板减少妊娠中,无论有否ICH史,必须确立ICH的风险。材料和方法 作者在MEDLINE检索了未经治疗的FNAIT妊娠的ICH病例。排除具有混淆因素的病例,在24篇报导中有27例母亲的62次妊娠符合条件。另外,包括在作者的病案记案中2例有5次妊娠的母亲。观察研究以评估没有ICH史的FNAIT妊娠中并发ICH的风险。结果
Background and Objective Fetal or neonatal intracranial hemorrhage (ICH) is a serious complication of fetal or neonatal alloimmune thrombocytopenia (FNAIT). In order to obtain a decision to prevent ICH, in consecutive thrombocytopenic pregnancies, regardless of the history of ICH, the risk of ICH must be established. Materials and Methods The authors searched MEDLINE for ICH cases of untreated FNAIT pregnancies. Excluding confounding cases, 27 pregnancies of 27 mothers met the criteria in 24 reports. In addition, 2 mothers with 5 pregnancies were included in the author’s medical record. Study to evaluate the risk of concurrent ICH in FNAIT pregnancies without a history of ICH. result