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[目的]研究延边地区朝鲜族、汉族肝硬化患者肝硬化程度与甲状腺功能变化的相关性。[方法]按Child-Pugh分级法将病例组分为A级组36例(朝鲜族19例、汉族17例)、B级组32例(朝鲜族15例、汉族17例)、C级组26例(朝鲜族15例、汉族11例);对照组38例。空腹采集静脉血并分离血清测甲状腺激素即游离三碘甲状腺原氨酸(FT3)和游离甲状腺素(FT4)。[结果]肝硬化组和对照组相比肝硬化患者甲状腺功能下降,并且肝硬化程度越严重甲状腺功能下降越明显,朝鲜族、汉族肝硬化患者甲状腺功能变化无差异。[结论]肝硬化患者甲状腺功能下降明显多预示肝硬化病情严重,肝硬化患者甲状腺功能下降与种族无相关性。
[Objective] To investigate the correlation between the degree of liver cirrhosis and thyroid function in Korean and Han nationality in Yanbian area. [Methods] According to the Child-Pugh grading method, the cases were divided into 36 cases (19 cases of Korean nationality and 17 cases of Han nationality), 32 cases of B group (15 cases of Korean nationality, 17 cases of Han nationality), 26 cases of C group Cases (Korean 15 cases, Han 11 cases); control group 38 cases. Venous blood was collected on fasting and serum was measured for thyroid hormones, namely free triiodothyronine (FT3) and free thyroxine (FT4). [Results] The thyroid function of patients with cirrhosis was significantly lower than that of patients with cirrhosis, and the more serious the degree of liver cirrhosis was, the more obvious the thyroid function decline was. There was no difference in the thyroid function between the patients with cirrhosis of the Korean and Han nationalities. [Conclusions] Decreased thyroid function in patients with cirrhosis is significantly higher than that in patients with cirrhosis. The decline of thyroid function in cirrhotic patients is not related to race.