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目的探讨新一代薄层液基细胞学检查(LPT)对宫颈病变的诊断价值,及时诊断宫颈癌及癌前病变。方法选择2007年1月至2009年6月因各种妇科疾病就诊于我院妇产科门诊行LPT检查的5426例患者,对宫颈LPT检查提示异常的209例患者全部在阴道镜下活检,以病理结果作为金标准,评价薄层液基细胞学检查在宫颈病变中的诊断价值。结果5426例LPT结果中,正常范围5216例(96.13%),阳性结果共计209例。209例患者阴道镜下活检,组织学结果为炎症或良性病变98例,CIN(宫颈上皮不典型增生)Ⅰ～Ⅱ75例,CINⅡ～Ⅲ及CIS 21例,SCC/AIS 5例。结论LPT检测对提高宫颈病变的诊断率有重要意义,是早发现、早预防宫颈癌发生的有力措施。
Objective To investigate the diagnostic value of a new generation of thin-section liquid-based cytology (LPT) for cervical lesions and diagnose cervical cancer and precancerous lesions in time. Methods From January 2007 to June 2009, 5426 patients with LPT examination in gynecology and obstetrics clinic in our hospital due to various gynecological diseases were selected. All 209 patients with abnormal cervical LPT examination underwent colposcopy biopsy. As the gold standard pathological results, evaluation of thin liquid-based cytological examination in the diagnosis of cervical lesions. Results Among the 5426 LPT cases, 5216 cases (96.13%) had normal range and 209 cases had positive results. The colposcopic biopsies of 209 patients with histopathology showed 98 cases of inflammatory or benign lesions, Ⅰ ~ Ⅱ of CIN (cervical epithelial dysplasia), 21 of CIN Ⅱ ~ Ⅲ and CIS, and 5 of SCC / AIS. Conclusion The detection of LPT is of great significance to improve the diagnosis rate of cervical lesions and is a powerful measure to prevent early detection of cervical cancer.