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作者观察20例革兰阴性(G~-)杆菌脑膜炎患者单用头孢羟羧氧酰胺(moxalactam)或联合应用其它抗生素的治疗效果,指出本药是治疗肠道G~-杆菌脑膜炎的高效剂。其死亡与严重的原发病有关。观察对象为20例1周至80岁经细菌学检查证明为G~-杆菌脑膜炎患者。其中假单孢菌与克雷伯氏杆菌混合感染1例,克雷伯氏杆菌9例、大肠杆菌6例,粘质沙雷氏菌2例,奇异变形杆菌及粘球杆菌各1例。药物剂量及疗程:4例儿童每天200mg/kg体重,1例每天100mg/kg体重,1例每天300mg/kg体重,
The authors observed the efficacy of moxalactam alone or in combination with other antibiotics in 20 patients with gram-negative bacillary meningitis, indicating that the drug is effective in treating G-meningitis in the gut Agent. Its death is associated with a serious primary disease. Observed in 20 cases from 1 week to 80 years old by bacteriological examination proved to be G ~ - meningitis patients. One case of Pseudomonas and Klebsiella pneumoniae mixed infection in 1 case, Klebsiella in 9 cases, Escherichia coli in 6 cases, Serratia marcescens in 2 cases, Proteus mirabilis and Mycobacterium in 1 case. Drug dosage and course of treatment: 4 cases of children daily 200mg / kg body weight, 1 day 100mg / kg body weight, 1 day 300mg / kg body weight,