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本文包括动物实验和人体研究两部分。以白色成年家兔为实验对象,给予不同频率、不同强度的振动负荷,在接振前和接振后15k、30天、60天测定SSEP、SCV、MCV的变化,并对大脑单胺类神经递质、肾上腺儿茶酚胺类激素和骨骼肌能量物质进行了分析。又以振动性白指患者、接振工人和健康人为对象,分别给予一定量的振动负荷,在负荷前后测定SSEP、BAEP和VEP,进行振动负荷前后的组间比较和自身对照分析。结果表明,上述指标在振动负荷后均发生不同程度的变化。说明在振动作用下,出现了中枢及外周神经功能和器质损害以及神经递质和某些能量物质的改变;可以确立振动性神经病这一新概念。在振动病防治研究中突破了振动性白指的局限性。
This article includes animal experiments and human studies in two parts. The adult white rabbits were used as experimental subjects, and the vibrational loads of different frequencies and intensities were given. The changes of SSEP, SCV and MCV were measured before and after the vibration at 15, 30 and 60 days. Neurotransmitters, adrenal catecholamines and skeletal muscle energy substances were analyzed. Vibration white refers to patients, vibration workers and healthy people as objects, respectively, to give a certain amount of vibration load, before and after the load determination of SSEP, BAEP and VEP, before and after the vibration load comparison and self-control analysis. The results show that these indexes all change to some extent after the vibration load. This shows that under the action of vibration, the central and peripheral nerve function and organ damage and changes of neurotransmitters and some energy substances appear; and a new concept of vibratory neuropathy can be established. In the prevention and treatment of vibration disease breakthrough in the vibration of the white index limitations.