论文部分内容阅读
稳定的含氟胂叶立德的合成已有一些报道,但对稳定的含氟胂叶立德反应性的研究却甚少。最近,我们报道了三氟乙酰基亚甲基三苯基胂(1a)和双(三氟乙酰基)亚甲基三苯基胂(2a)的合成,发现这二个含氟胂叶立德非常稳定,难于和醛、酮反应。通过对1a的晶体结构的测定,证实了其稳定性。本文将前报道的方法扩展,可以用来合成多氟酰基胂叶立德1以及双(多氟酰基)胂叶立德(2). 亚甲基三苯基胂与全氟酰氯在各种条件下进行反应,都未能得到全氟酰基亚甲基三苯基胂,但在乙醚中,于-78℃至室温下与多氟羧酸酯反应,可以顺利地得到多氟酰基亚甲基三苯基胂(1)。在这里,酰化必需用多氟羧酸酯。
The synthesis of stable arsonium ylide has been reported, but there is little research on the stability of the fluorine-containing arsonium ylide. Recently, we reported the synthesis of trifluoroacetylmethylenetriphenylarsine (1a) and bis (trifluoroacetyl) methylenetriphenylarsine (2a) and found that these two fluorine-containing arsonium ylides were very stable , Difficult to react with aldehydes, ketones. The crystal structure of 1a was confirmed by its stability. In this paper, the previously reported method is extended and can be used to synthesize polyfluoroacyl arsonium ylide 1 and bis (polyfluoroacyl) arsonium ylide 2. Methylenetriphenylarsine reacted with perfluoroacyl chloride under various conditions, Had failed to obtain perfluoroacylmethylenetriphenylarsine, but was allowed to react with polyfluorocarboxylate in diethyl ether at -78 ° C to room temperature to obtain polyfluoroacylmethylenetriphenylarsine ( 1). Here, it is necessary to use polyfluorocarboxylates for the acylation.