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Aztreonam(AZT),系美国Squibb公司首创的一种单环β-内酰胺抗生素。作者用AZT单独治疗严重的小儿化脓性髓膜炎12例,其中男9例,女3例。年龄从2个月至8岁另11个月。病原菌如下:2例为脑膜炎奈瑟氏菌,3例为大肠杆菌,6例为嗜血流感杆菌,1例病原菌不明。给药量:每日134～400mg/kg,分3～4次使用,用药持续10～28日结果:1.临床效果12例病人中,5例显效,7例有效,总有效率100%。
Aztreonam (AZT), a monocyclic beta-lactam antibiotic pioneered by Squibb in the United States. Authors treated with AZT alone severe purulent sepsis in 12 children, 9 males and 3 females. Age from 2 months to 8 years and the other 11 months. Pathogenic bacteria are as follows: 2 cases of Neisseria meningitidis, 3 cases of Escherichia coli, 6 cases of Haemophilus influenzae, 1 case of unknown pathogens. Dosage: 134 ~ 400mg / kg daily, divided into 3 to 4 times, medication continued for 10 to 28 days Results: 1. Clinical results 12 patients, 5 cases markedly effective in 7 cases, the total effective rate of 100%.