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抗生素是目前世界上药品中消费量最大,临床使用最广泛的一类化疗药物,它为人类控制感染性疾病发挥了重要的作用。但是,由于抗生素的普遍应用,也相应地带来了许多新的问题,如抗生素对正常菌群生态平衡的影响,细菌耐药性的变迁所导致耐药菌的感染病增多,尤其是在病原菌集中分布的医院环境中,抗生素的大量应用将会增加医院内感染的危险性。本文就抗生素的应用和医院内感染的关系作一简述。
Antibiotics are currently the largest and most widely used type of chemotherapeutic drugs in medicine in the world. They play an important role in human control of infectious diseases. However, due to the widespread application of antibiotics, many new problems have been brought forth correspondingly, such as the impact of antibiotics on the ecological balance of normal flora and the increase of bacterial resistance caused by the change of bacterial resistance, especially in the concentration of pathogens In a distributed hospital environment, a large number of antibiotic applications will increase the risk of nosocomial infections. This article gives a brief account of the relationship between the use of antibiotics and nosocomial infections.