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探讨胃溃汤(GU)、十二指肠球部溃疡(DU)、胃切除后吻合口炎(PGAS)、溃疡型胃癌(UGC)及慢性萎缩性胃炎(GAG)患者血浆胃动素(MTL)的变化意义。采田非平衡放射免疫法测定血浆MTL。结果显示血浆MTL水平自高而低依次为UGC组(487.9±22.31ng/L).PGAS组(484.0±259.5ng/L),DU组(468.8±226.1ng/L).GU组(444.8±220.8ng/L),CAG组(362.1±250.2ng/L)。前4组与对照组相比差异有显著性(P<0.01)。而CAG组与对照组相比差异无显著性(P>0.05)。认为UGC,PGAS,DU,GU患者MTL升高与胃粘膜完整性破坏造成MTL的调控失调有关。
(MT) in patients with gastric ulcer (GU), duodenal ulcer (DU), anastomotic stoma after gastrectomy (PGAS), ulcerative gastric cancer (UGC) and chronic atrophic gastritis ) Change meaning. Non - equilibrium radioimmunoassay for determination of plasma MTL in field. The results showed that the plasma levels of MTL from high to low were UGC group (487.9 ± 22.31ng / L), PGAS group (484.0 ± 259.5ng / L), DU group (468.8 ± 226.1ng / L), GU group (444.8 ± 220.8) ng / L), CAG group (362.1 ± 250.2ng / L). There were significant differences between the first 4 groups and the control group (P <0.01). There was no significant difference between CAG group and control group (P> 0.05). That UGC, PGAS, DU, GU patients with elevated MTL and gastric mucosal integrity caused by the destruction of MTL regulation disorders.