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目的评价3种治疗儿童社区获得性肺炎方案的经济学效果。方法将118例肺炎患儿随机分为头孢呋辛治疗组(A),头孢曲松治疗组(B)和头孢噻肟治疗组(C),运用药物经济学的成本-效果分析方法进行比较。结果 3种治疗方案有效率分别为72.50%、84.62%和87.18%(P>0.05),成本分别为(1110.46±156.26)元、(1110.80±120.27)元和(2405.52±325.36)元(P<0.05);成本-效果比分别为15.32%、13.13%、27.59%;3组均未出现严重的不良反应。结论头孢曲松治疗儿童社区获得性肺炎经济合理。
Objective To evaluate the economic effects of three treatments for children with community-acquired pneumonia. Methods 118 cases of children with pneumonia were randomly divided into cefuroxime treatment group (A), ceftriaxone treatment group (B) and cefotaxime treatment group (C), and compared with the cost-effectiveness analysis method of pharmacoeconomics. Results The effective rates of the three treatment regimens were 72.50%, 84.62% and 87.18%, respectively (P <0.05), and the costs were 1110.46 ± 156.26 yuan, 1110.80 ± 120.27 yuan and 2405.52 ± 325.36 yuan respectively ). The cost-effectiveness ratios were 15.32%, 13.13% and 27.59% respectively. No serious adverse reactions occurred in the three groups. Conclusion Ceftriaxone treatment of children with community-acquired pneumonia is economical and reasonable.