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F30385,β-(5-硝基-2-呋喃)丙烯(N-一氮六环-1-乙基)酰胺盐酸盐,对小白鼠、兔及犬体內的童虫的杀虫作用显著比杀成虫的作用为强。兔及犬于感染尾蚴后7天和14天,兔按100毫克/公斤/日,犬按50毫克/公斤/日的剂量连服药2天,最后发育的成虫数比对照组减少86—100%,部分动物完全治愈。以等毒性剂量比较F30385与F30066对小白鼠及兔体內童虫的杀虫作用的结果,F30385强于F30066。
F30385 and β-5- (5-nitro-2-furan) propene (N-azacyclohexyl-1-ethyl) amide hydrochloride have significant insecticidal effects on the pest in mice, rabbits and dogs More effective than killing adults. Rabbits and dogs were infected with cercariae 7 days and 14 days after the rabbits at 100 mg / kg / day, dogs at 50 mg / kg / day dosage even medication for 2 days, the final development of the adult population than the control group decreased 86-100% Some animals are completely cured. F30385 was stronger than that of F30066 at the same toxic dose to compare the insecticidal effect of F30385 and F30066 on the schistosomula in mice and rabbits.