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应用二维多普勒超声心动图对６８例急性心肌梗塞（ＡＭＩ）患者的左室重构（ＬＶＲ）变化进行了观察。结果显示，心肌梗塞后ＬＶＲ早期（３～６周）左室舒张末内径（ＬＶＤｄ）、左室舒张末容积（ＥＤＶ）、左室收缩末容积（ＥＳＶ）、左室收缩期最大室壁应力（Ｅｄｂ）、左室收缩末期室壁应力（Ｅｓｂ）、平均室壁应力（ｍｅａｎｂ）、二尖瓣舒张晚期血流速度峰值（ＰＶＡ）、左房张力（ＬＡＴ）、左房射血力（ＬＡＦ）及峰值充盈速度（ＰＦＲ）显著增大（Ｐ＜０．０１－０．００１），射血分数（ＥＦ）、心输出量（ＣＯ）、左室收缩期圆周指数（ＬＶＳＣＩ）、平均周边纤维缩短速率（ＭＶＣＦ）、二尖瓣舒张早期血流速度峰值（ＰＶＥ）及ＰＶＡ／ＰＶＥ显著降低（Ｐ＜０．０１－０．００１）。ＬＶＲ晚期（６－１２个月），ＥＤＶ、ＥＳＶ增加，ＥＦ、ＣＯ及ＬＶＳＣＩ降低（Ｐ＜０．００１）；与ＬＶＲ早期比较，ＰＶＥ、ＰＶＡ及ＬＡＦ无显著性差异（Ｐ＞０．０５）。提示ＡＭＩ后ＬＶＲ的主要病因是梗塞区膨展、左室扩张、容量负荷及室壁应力增加，从而导致心肌梗塞并发症；ＥＳＶ、ＥＤＶ及ＥＦ可作为了解远期ＡＭＩ患者预后的最佳指标。
The changes of left ventricular remodeling (LVR) in 68 patients with acute myocardial infarction (AMI) were observed by two-dimensional Doppler echocardiography. The results showed that left ventricular end-diastolic diameter (LVDd), left ventricular end-diastolic volume (EDV), left ventricular end-systolic volume (ESV), left ventricular systolic maximum wall stress Edb, Esb, meanb, PVA, LAT and LAF in late stage of left ventricular end systolic pressure, (P <0.01-0.001), ejection fraction (EF), cardiac output (CO), left ventricular systolic index (LVSCI), mean peripheral fiber shortening (MVCF), mitral early diastolic flow velocity peak (PVE) and PVA / PVE decreased significantly (P <0.01-0.001). There was no significant difference in PVE, PVA and LAF between early LVR (6-12 months), EDV, ESV, EF, CO and LVSCI (P <0.001) . It is suggested that the main causes of LVR after AMI are the expansion of infarction area, left ventricular dilatation, volume load and increase of wall stress, leading to the complication of myocardial infarction. ESV, EDV and EF can be used as the best indexes to understand the prognosis of AMI patients.