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染色体显带技术对正常及异常染色体的准确识别是很有用的。虽然常规G、R及Q显带均能识别染色体改变,但也有局限性,尤其在瘤细胞中重排染色体非常复杂时更如此。比较新的显带技术,如DA/DAPI染色,能选择性显示染色体特定区段,是判明标记染色体来源和在易位中识别确切断点的好方法。如果断点位于或靠近着丝粒区,常用C显带法检测染色体易位的性质。然而,在骨髓染色体中很难获得高质
Chromosome banding techniques are useful for accurate recognition of normal and abnormal chromosomes. Although conventional G, R, and Q banding both recognize chromosomal alterations, they have limitations, especially when the chromosomal rearrangement in tumor cells is very complex. The newer banding techniques, such as DA / DAPI staining, that selectively display chromosome-specific segments are a good way to identify the source of the marker chromosome and identify the exact breakpoint in the translocation. If the breakpoint is located at or near the centromere region, C-banding is commonly used to detect chromosomal translocations. However, high quality is difficult to obtain in bone marrow chromosomes