全球使用脊髓灰质炎病毒灭活疫苗的经验

• 作 者: 杨俊峰
• 出 处: 中国疫苗和免疫
• 发表日期: 2009年01期
• 关键词: 脊灰 联合疫苗 抗体阳转率 Vaccine 免疫原性 抗体持久性 脊灰疫苗 血清抗体 常规接种 疫苗接种率

口服脊髓灰质炎(脊灰)减毒活疫苗(Oral Poliomylitis Attenuate Live Vaccine,OPV)是全球消灭脊灰的战略,OPV已大幅度降低全球脊灰的发病率。然而,由于疫苗相关麻痹型脊灰(Vaccine As-sociated Paralytic Poliomyelitis,VAPP)和疫苗衍生脊灰病毒(Vac-cine-derived Poliovirus,V

The Oral Poliomyelitis Attenuate Live Vaccine (OPV) is a global polio eradication strategy that has dramatically reduced the incidence of polio in the world. However, due to the fact that Vaccine As-sociated Paralytic Poliomyelitis (VAPP) and Vaccine-derived Poliovirus (V