论文部分内容阅读
1979年日本的抗生索研究相当活跃,现将日本国内发表的有关抗生素的论文报告归纳如下。一、有关β-内酰胺抗生素的研究作为有抑制β-内酰胺酶活性的第三代抗生素,引入注目的是一类橄榄酸(olivanic acid)有关于它们的发酵、检定、分离等的详细报告。弄清了包括MM4550在内的一类橄榄酸复合物的筛选、发酵、分离、理化和生物学性质。而且在培养橄榄色链霉菌ATCC31365时,通过限制培养基内的Na_2SO_4浓度,发现了新型同类物质MM22380、MM22381、MM22382、MM
In 1979 Japan’s antibiotic cable research quite active, now published in Japan on antibiotics thesis report summarized as follows. I. STUDIES ON β-LACTAM ANTIBIOTICS The third generation of antibiotics that inhibit β-lactamase activity has drawn attention to a detailed report of a class of olivanic acids regarding their fermentation, assay, isolation, etc. . To clarify the screening, fermentation, separation, physicochemical and biological properties of a class of olive acid complexes including MM4550. Moreover, in the culture of Streptomyces voltaicus ATCC31365, the novel congeners MM22380, MM22381, MM22382, MM