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骨质疏松患者人工关节置换后,感染是手术后严重的并发症之一,它延长治疗进程,增加医疗开支,降低治疗效果,常常导致手术彻底失败,或造成病人残废,严重者甚至死亡。载药人工骨作为一种有效的辅助治疗措施,已被广泛应用于慢性骨髓炎等临床治疗,并在人工关节术后感染的防治上发挥越来越重要的作用。该文就人工关节感染的特性,载药人工骨的分类及其作用、潜在缺点,以及在预防人工关节感染中的病例选择做一综述。
Osteoporosis patients after artificial joint replacement, infection is one of the serious complications after surgery. It prolongs the treatment process, increases the medical expenses and reduces the treatment effect. It often leads to the complete failure of the operation or the disability of the patient or even the serious death. As an effective adjuvant therapy, drug-loaded artificial bone has been widely used in clinical treatment of chronic osteomyelitis and plays an increasingly important role in prevention and treatment of artificial joint infection. This article reviews the characteristics of artificial joint infections, the classification of drug-loaded artificial bones and their effects, potential shortcomings, and the selection of cases in the prevention of artificial joint infections.