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观察 14 5例 11~ 14周孕妇 ,随机分为服药组 74例 ,给予米非司酮 2 5 mg,饭前、饭后 2 h口服 ,1天 2次 ,连服 3天 ,第 4天米索前列醇 60 0 μg,口服或给予阴道后穹窿放置后清宫或钳刮。对照组 71例放置宫颈扩张物或直接钳刮术。结果两组的宫颈软化及宫口扩张情况差异有显著性 ( P<0 .0 0 5 )。两组术中综合反应程度差异有显著性 ( P<0 .0 0 5 )。术时出血量比较差异有非常显著性( P<0 .0 1)。对孕 11~ 14周人流月份偏大者服用米非司酮和米索前列醇后再清宫或钳刮 ,疗效显著、副作用小、医务人员便于操作和孕妇易于接受。
Forty-five pregnant women, 11-14 weeks old, were randomly divided into medication group (n = 74), mifepristone 25 mg, orally before meals and 2 h after meals, twice a day for 3 days and 4 days Soprostigum 60 0 μg, given orally or vaginal posterior fornix or forceps. 71 cases of control group placed cervical dilatation or direct clamp curettage. Results There was significant difference in cervical softening and uterine dilatation between the two groups (P <0.05). There was a significant difference in the comprehensive response between the two groups (P <0.05). The amount of bleeding during surgery was significantly different (P <0.01). Pregnancy 11 to 14 weeks of large flow of people taking mifepristone and misoprostol or curettage after curettage, significant effect, side effects, easy to operate and pregnant women medical staff to accept.