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血清组织型纤溶酶原激活剂(t-PA)是体内纤溶系统的关键成份。维持体内纤溶及凝血两个系统的平衡,防止血栓形成起到重要作用。血清t—PA主要由血管内皮细胞及组织细胞合成的,它转变纤溶酶原为活化的纤溶酶。血清t-PA被肝脏摄取清除,某些肿瘤组织如肝癌乳腺癌等能大量合成
Serum tissue-type plasminogen activator (t-PA) is a key component of the fibrinolytic system in vivo. Maintaining the balance of the two systems of fibrinolysis and coagulation in the body prevents thrombosis from playing an important role. Serum t-PA is mainly synthesized by vascular endothelial cells and tissue cells, which convert plasminogen to activated plasmin. Serum t-PA is cleared up by the liver, some tumor tissues such as liver cancer can be a large number of synthetic breast