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以1989年10月31日~1994年11月1日就诊的类风湿性关节炎(RA)患者为对象,分为布西拉明(Bucillarnine,以下简称B)+柴苓汤(S)、B,S三组,各25例。作为治疗效果,测定Lansbury指数(LI)、ESR,CRP,RAHA,各种Ig值、免疫复合物(IC);作为副作用,测定蛋白尿、肾活检电子显微镜检查、肾Cu,Zn-SOD活性值、肾谷胱甘肽(GSH)相关物质、活性氧的变化。结果:B+S组,LI,ESR,CRP,RAHA等RA炎症症状及自身抗体比单独用药时明显受到抑制;并用时IgG,
The patients with rheumatoid arthritis (RA) treated on October 31, 1989 to November 1, 1994 were divided into Bucillarin (B) + Chailing Decoction (S), B , S three groups, each 25 cases. As a therapeutic effect, Lansbury Index (LI), ESR, CRP, RAHA, various Ig values, immune complexes (ICs) were measured; proteinuria was measured as a side effect; renal biopsy electron microscopy; , Renal glutathione (GSH) -related substances, reactive oxygen species changes. Results: Inflammatory symptoms and autoantibodies such as LI, ESR, CRP and RAHA were significantly inhibited in B + S group compared with those in single administration,