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苏拉明是一种抗锥体虫药。对激素不敏感的前列腺癌的Ⅱ期临床试验效果令人满意。Thalmann等在鼠体内研究表明，苏拉明通过非雄激素依赖作用降低了转移性前列腺癌C4-2的前列腺特异抗原（PSA）的表达，而苏拉明并没有抑制肿瘤增殖，因此，把PSA作为苏拉明对激素不敏感前列腺癌的
Suramin is an ant cone drug. Phase II clinical trials of hormone-insensitive prostate cancer are promising. Thalmann et al. In vivo studies in rats showed that suramin reduced prostate-specific antigen (PSA) expression in metastatic prostate cancer C4-2 through androgen deprivation, whereas suramin did not inhibit tumor proliferation. Thus, PSA As suramin hormone-insensitive to prostate cancer