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目的:探讨子痫前期及子痫并发可逆性后部白质脑病(RPLS)患者临床表现与影像学的关系。方法:回顾性分析盛京医院2008年1月~2011年6月20例子痫前期及子痫并发RPLS患者的影像学及临床资料。结果:20例患者均行头部MRI或CT检查,其中出现顶叶病变18例、枕叶病变10例、额叶病变5例、基底节病变6例、颞叶病变2例、侧脑室旁病变3例、小脑病变2例、岛叶皮层及半卵圆区各1例。20例患者中,4例患者行增强扫描,均显示病灶无强化;6例患者行磁共振静脉血管成像(MRV),未发现静脉窦血栓形成;3例行磁共振动脉血管成像(MRA),未见动脉血管异常;11例在初次行头部MRI后4~47天复查头部MRI,10例患者完全恢复,1例患者绝大部分恢复。所有患者临床症状均恢复良好,无严重后遗症出现。结论:结合患者病史特点、临床表现及影像学改变,RPLS诊断并不困难,早期积极治疗患者预后良好。
Objective: To investigate the relationship between clinical manifestations and imaging in patients with reversible posterior segment leukoencephalopathy (RPLS) complicated by preeclampsia and eclampsia. Methods: The imaging and clinical data of 20 patients with preeclampsia and eclampsia complicated with RPLS in Shengjing Hospital from January 2008 to June 2011 were retrospectively analyzed. Results: Twenty patients underwent MRI or CT scans. Among them, there were 18 cases of parietal lesions, 10 cases of occipital lobe lesions, 5 cases of frontal lobe lesions, 6 cases of basal ganglia lesions, 2 cases of temporal lobe lesions, 3 cases, cerebellar lesions in 2 cases, island cortex and semi-oval in 1 case. Among the 20 patients, 4 patients underwent enhanced scan, all showed no enhancement of the lesion. Six patients underwent magnetic resonance venography angiography (MRV), no sinus venous thrombosis was found. Three patients underwent magnetic resonance angiography (MRA) No arterial vascular abnormalities were observed in 11 cases. MRI was performed on the first 4 to 47 days after the head MRI was performed in the first time, and 10 patients recovered completely. Most of the patients recovered. Clinical symptoms of all patients recovered well without serious sequelae. Conclusion: Combined with the characteristics of patient history, clinical manifestations and imaging changes, RPLS diagnosis is not difficult, early active treatment of patients with good prognosis.