自然获得麻风的黑猩猩的血清学研究

• 作 者: 张伟云
• 出 处: 国外医学.皮肤病学分册
• 发表日期: 1992年05期
• 关键词: 血清学 IgG 抗原检测 笼饲 间接接触 合成抗原 曲线轮廓 滴度 临床症状 抗酸菌

作者对两只自然感染麻风的黑猩猩(编号2038及PTT229)作了长期的纵向的血清学研究,并对160只与它们同笼饲养的黑猩猩以及其他可能与它们有间接接触的黑猩猩作了ELISA检测,以估计感染麻风的时间。用天然PGL-1和LAM抗原测黑猩猩血清中IgG和IgM抗体。阳性结果分别为:抗PGL-1 IgG4例(2.5%),IgM5例(3.1%);

The authors made long-term longitudinal serological studies of two leprosy chickens naturally infected with leprosy (Nos. 2038 and PTT229) and performed ELISA tests on 160 chimpanzees caged with them and other chimpanzees possibly in indirect contact with them To estimate the time of infection with leprosy. IgG and IgM antibodies in chimpanzee serum were measured using native PGL-1 and LAM antigens. Positive results were as follows: anti-PGL-1 IgG4 cases (2.5%), IgM5 cases (3.1%);