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目的 :提高肾上腺皮质癌的诊治水平。方法 :回顾分析 12例肾上腺皮质癌的临床诊治资料。结果 :功能性肿瘤 8例 ,主要以柯兴综合征为主 ,性征异常者及原发性醛固酮增多症相对少见。无功能性肿瘤 4例。影像学检查显示肿瘤大小 5 5～ 18 5cm ,平均 7 5cm。CT和MRI提示肿瘤边界不规则 ,内部质地不均匀。 12例均行肾上腺癌根治性手术 ,3年生存率2 5 %。结论 :影像学检查结合临床表现可以对肾上腺皮质癌作出诊断。根治性手术是肾上腺皮质癌有效的治疗方法
Objective: To improve the diagnosis and treatment of adrenocortical cancer. Methods: The clinical data of 12 adrenocortical carcinomas were retrospectively analyzed. Results: There were 8 cases of functional tumor, mainly Cushing ’s syndrome, with abnormal sexual signs and primary aldosteronism relatively rare. No functional tumor in 4 cases. Imaging examination showed a tumor size of 5 5 ~ 18 5cm, an average of 7 5cm. CT and MRI tips irregular tumor boundaries, the internal texture is not uniform. Twelve cases underwent radical surgery for adrenal cancer with a 3-year survival rate of 25%. Conclusion: Radiographic examination combined with clinical manifestations can make a diagnosis of adrenocortical cancer. Radical surgery is an effective treatment for adrenal cortical cancer