论文部分内容阅读
目的:探讨不同剂量舒芬太尼用于全麻患儿喉罩插入前麻醉诱导效果及安全性的差异。方法:选取我院骨科2011年6月至2013年1月收治的行全麻喉罩插入患儿90例,采用随机数字表法分为A、B、C三组各30例,喉罩插入前分别给予0.1、0.2、0.3μg/kg舒芬太尼复合2.5 mg/kg丙泊酚行麻醉诱导,比较三组患儿喉罩一次插入成功率、喉罩插入时间、呼吸暂停时间、喉罩插入评分满意度,诱导前(T0)、诱导后(T1)、喉罩插入时(T2)、喉罩插入1 min(T3)及喉罩插入5 min(T4)血流动力学指标水平等。结果:三组患儿喉罩一次插入成功率和喉罩插入时间比较差异无统计学意义(P>0.05);B、C组患儿呼吸暂停时间长于A组,且C组长于B组(P均<0.05);B、C组患儿张口度、插入阻力、吞咽、呛咳或憋气及身体活动度等喉罩插入评分满意度均高于A组(P<0.05);三组患儿T1时MAP和HR水平均低于T0时(P<0.05),A组患儿T2时MAP和HR水平均高于T0时及B、C组(P<0.05),三组患儿T4时MAP和HR水平均低于T0时(P<0.05)。结论:0.2μg/kg舒芬太尼用于全麻患儿喉罩插入前麻醉诱导能够有效改善插入效果,稳定机体血流动力学,可作为临床应用最佳剂量。
Objective: To investigate the effect and safety of different doses of sufentanil in induction anesthesia before laryngeal mask insertion in children with general anesthesia. Methods: Totally 90 children with general anesthesia were enrolled in our hospital from June 2011 to January 2013. The patients were divided into three groups (A, B and C) The rats were anesthetized with 0.1,0.2,0.3μg / kg sufentanil and 2.5 mg / kg propofol respectively. The successful rate of laryngeal mask insertion, laryngeal mask insertion time, apnea time, laryngeal mask insertion (T0), post-induction (T1), laryngeal mask insertion (T2), laryngeal mask insertion 1 min (T3) and laryngeal mask insertion 5 min (T4) hemodynamic parameters and so on. Results: There was no significant difference in the success rate of laryngeal mask insertion between one group and the laryngeal mask in the three groups (P> 0.05). The duration of apnea was longer in group B and group C than in group A (P <0.05). The satisfaction degree of laryngeal mask insertion in group B and C were higher than those in group A (P <0.05). The T1, T1, (P <0.05). MAP and HR of T2 group were significantly higher than those of T0 and B, C group (P <0.05) HR levels were lower than T0 (P <0.05). CONCLUSIONS: Sufentanil at 0.2μg / kg can be used to induce anesthesia before induction of laryngeal mask in general anesthesia, which can effectively improve the insertion effect and stabilize the hemodynamics of the body, which can be used as the best dose for clinical application.