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目的比较早期静脉溶栓与动脉溶栓在急性脑梗死治疗中的临床疗效,选择最佳的治疗途径。方法静脉溶栓静脉滴注尿激酶;动脉溶栓从股动脉插管至血管闭塞部位,局部注射尿激酶。结果静脉组76例,显效率57.89%,总有效率81.58%,并发脑出血4例,死亡2例;动脉组41例,显效率82.93%,总有效率100%,无出血及其它严重并发症。两组相比有显著性差异(P<0.05)。结论超选择动脉溶栓治疗急性脑梗死安全可靠,疗效明显优于静脉溶栓。
Objective To compare the clinical efficacy of early intravenous thrombolysis and arterial thrombolysis in the treatment of acute cerebral infarction and select the best treatment. Methods Intravenous thrombolysis with intravenous infusion of urokinase; arterial thrombolysis from the femoral artery to the vascular occlusion site, local injection of urokinase. Results In venous group, 76 cases showed markedly effective rate of 57.89%, total effective rate of 81.58%, 4 cases of intracerebral hemorrhage and 2 deaths. In arterial group, 41 cases showed markedly effective rate of 82.93% and total effective rate of 100% without bleeding and other serious complications . There was significant difference between the two groups (P <0.05). Conclusion Superselective arterial thrombolysis is safe and reliable in treating acute cerebral infarction, and the curative effect is better than intravenous thrombolysis.