论文部分内容阅读
分别给小鼠i.p.人参茎叶皂甙(SSLG)30～100mg/kg,连续3～10天,可减少小鼠在跳台法中错误反应次数,在食物迷宫法中,可减少小鼠行走方向错误并缩短寻找到食物的时间。增加小鼠脑内去甲基肾上腺素(NE)和多巴胺(DA)的含量,减少5-羟色胺(5-HT)的含量。减少B型单胺氧化酶(MAO-B)的活性和过氧化脂质(LPO)水平。结果提示人参茎叶皂甙具有一定的增强记忆、延缓衰老的作用。
The mice were given ip ginseng stem and leaf saponin (SSLG) 30 to 100 mg/kg for 3 to 10 consecutive days to reduce the number of erroneous responses in the step-by-step approach. In the food lab maze, the walking direction of the mice was reduced and Reduce the time to find food. Increases the content of norepinephrine (NE) and dopamine (DA) in the brain of mice and decreases the content of 5-hydroxytryptamine (5-HT). Reduction of B-type monoamine oxidase (MAO-B) activity and lipid peroxidation (LPO) levels. The results suggest that ginseng stem and leaf saponins have a certain role in enhancing memory and delaying aging.