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目的探讨宫腔镜下子宫内膜息肉切除术联合左炔诺孕酮宫内缓释系统(曼月乐)治疗子宫内膜息肉的疗效及安全性。方法总结、分析120例患者经宫腔镜下切除及术后放置曼月乐治疗子宫内膜息肉的临床及随访资料。结果全部患者宫腔镜手术均顺利完成,无手术并发症发生,术后病理结果为子宫内膜息肉,排除子宫内膜恶性病变,于术后7~10 d放置曼月乐。所有患者随访满2年,患者月经模式改变,月经过多者月经量明显减少,血红蛋白值明显升高,手术前与手术后子宫内膜厚度各组间比较差异均有统计学意义(P<0.001);无病例复发;无明显不良反应发生。结论宫腔镜下切除及术后应用左炔诺孕酮宫内缓释系统治疗子宫内膜息肉临床效果肯定,可抑制子宫内膜增长,随访无复发病例,安全、有效,值得临床推广。
Objective To investigate the efficacy and safety of hysteroscopic endometrial polypectomy combined with levonorgestrel intrauterine system (Mirena) in the treatment of endometrial polyps. Methods: To summarize and analyze the clinical and follow-up data of 120 cases of endometrial polyps after hysteroscopic resection and postoperative placement of Mirena. Results All patients underwent hysteroscopic surgery without complications. The pathological results were endometrial polyps and the endometrial malignant lesions were excluded. Mirena was placed at 7-10 days after operation. All patients were followed up for 2 years, the patient’s menstruation pattern changed, menorrhagia menorrhagia decreased significantly, hemoglobin value increased significantly, preoperative and postoperative endometrial thickness between the various groups were statistically significant (P <0.001 ); No case of recurrence; no significant adverse reactions. Conclusion Hysteroscopic resection and postoperative application of levonorgestrel intrauterine system in the treatment of endometrial polyps affirmed the clinical effect, can inhibit the growth of the endometrium, no recurrence of cases, safe and effective, worthy of clinical promotion.