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目的研究并分析托吡酯治疗小儿癫痫的临床疗效与安全性。方法选取我院门诊2008年12月1日-2012年10月1日间收治的88例小儿癫痫症患者,随机分为两组各44例。观察组用托吡酯治疗,对照组用丙戊酸钠治疗,分析两组患者的临床疗效与安全性。结果观察组临床疗效优于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论运用托吡酯治疗小儿癫痫安全有效,且价格低廉,值得推广。
Objective To study and analyze the clinical efficacy and safety of topiramate in treating children with epilepsy. Methods Eighty-eight children with epilepsy admitted to our hospital from December 1, 2008 to October 1, 2012 were randomly divided into two groups of 44 patients. The observation group was treated with topiramate, the control group was treated with sodium valproate, the clinical efficacy and safety of the two groups were analyzed. Results The clinical curative effect of the observation group was better than that of the control group, the incidence of adverse reactions was lower than that of the control group, the difference was statistically significant (P <0.05). Conclusion The use of topiramate in the treatment of children with epilepsy is safe and effective, and the price is low, it is worth promoting.