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目的通过对急性脑梗死(ACI)患者血清C-反应蛋白(CRP)和纤维蛋白原(Fib)水平检测,探讨其临床应用价值。方法对65例急性脑梗死患者及30例正常对照组的CRP和Fib分别采用免疫透射比浊法和凝结法进行检测。结果急性脑梗死患者的CRP和Fib水平均显著高于正常对照组(P<0.01);急性脑梗死完全康复组CRP和Fib入院时与痊愈出院时比较差异具有统计学意义(P<0.01),不完全康复组CRP和Fib入院时与出院时比较差异无统计学意义(P>0.05)。结论 CRP和Fib水平对评估急性脑梗死患者病情和愈后有着重要的临床意义。
Objective To investigate the clinical value of serum C-reactive protein (CRP) and fibrinogen (Fib) levels in patients with acute cerebral infarction (ACI). Methods CRP and Fib in 65 patients with acute cerebral infarction and 30 normal controls were detected by immunoturbidimetry and coagulation. Results The levels of CRP and Fib in patients with acute cerebral infarction were significantly higher than those in normal control group (P <0.01). The CRP and Fib levels in complete recovery group were significantly lower than those in control group (P <0.01) There was no significant difference in CRP and Fib admission and discharge at incomplete rehabilitation group (P> 0.05). Conclusion The levels of CRP and Fib have important clinical significance in evaluating the prognosis and prognosis of patients with acute cerebral infarction.