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目的观察热牙胶充填治疗慢性牙髓炎的效果。方法将110例慢性牙髓炎患者随机分为对照组和观察组,每组55例。对照组给予冷侧压充填治疗,观察组给予热牙胶充填治疗。分别记录两组填充用时,评估填充治疗前后咬合功能、检测血清白细胞介素1β(IL-1β),治疗后3个月评估临床疗效,观察两组不良反应情况。随访2~23个月,观察两组复发情况。采用SPSS 17.0统计软件。计量资料以x±s表示,比较采用t检验;计数资料以百分比表示,比较采用χ2检验。P<0.05为差异有统计学意义。结果观察组填充用时为(79.2±18.7)s,对照组为(198.8±28.9)s,两组比较P=0.000 4。两组治疗后咬合功能均提高,血清IL-1β水平均下降,且观察组上述改变均较对照组明显,组间比较P均<0.05。观察组总有效率为98.18%(54/55),对照组为85.45%(47/55),两组比较P=0.000 1。观察组不良反应发生率为1.81%,对照组为14.55%,两组不良反应发生率比较P=0.000 0。结论热牙胶充填治疗可有效改善慢性牙髓炎患者咬合功能,抑制炎症反应,且不增加不良反应。
Objective To observe the effect of hot tooth glue filling on chronic pulpitis. Methods 110 cases of chronic pulpitis were randomly divided into control group and observation group, 55 cases in each group. The control group was given cold lateral pressure and the observation group was given hot dentin filling. The two groups were filled with time to evaluate the bite function before and after the filling treatment, serum interleukin 1β (IL-1β) was measured, clinical efficacy was evaluated 3 months after treatment, and the adverse reactions were observed. Followed up for 2 ~ 23 months, observed the recurrence of two groups. Using SPSS 17.0 statistical software. Measurement data to x ± s said, compared with t test; count data expressed as a percentage, compared with the χ2 test. P <0.05 for the difference was statistically significant. Results The time of filling in the observation group was (79.2 ± 18.7) s and that in the control group was (198.8 ± 28.9) s, P = 0.000 4 in both groups. After treatment, the bite function increased and the level of serum IL-1β decreased. The above changes in the observation group were more obvious than those in the control group, both P <0.05. The total effective rate was 98.18% (54/55) in the observation group and 85.45% (47/55) in the control group, P = 0.0001 in both groups. The incidence of adverse reactions in the observation group was 1.81% and in the control group was 14.55%. The incidence of adverse reactions in the two groups was P = 0.000 0. Conclusion The treatment of hot tooth glue can effectively improve the occlusal function of patients with chronic pulpitis, inhibit the inflammatory reaction, and does not increase the adverse reaction.