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高血压合并左心室肥厚早已被人熟知。近年来研究发现左室心肌质量的增加伴随着血压明显增高达９０百分位或以上在儿童时期即已出现。一般认为左室心肌质量的增加是高血压或血压偏高的结果。仅在最近几年才有少数作者发现左室心肌质量的增加出现在儿童发生血压增高之前。血压正常儿童或青少年之父母有高血压者，其左室心肌质量均高于无高血压家族史者。本研究者在观察血压增高与高血压家族史及左室心肌质量之间的关系时，结果发现在高血压高危儿童并有家族史者左室心肌质量高于高血压高危儿童无高血压家族史者，提示除血压增高可能为左室心肌质量增加之原因外，而且左室心肌质量之增加尚可能为高血压之原因，即有可能在先天因素中存在左室心肌质量易于增加的因子或者说不能除外心室肌异常基因的存在。
Hypertension with left ventricular hypertrophy has long been known. In recent years, studies have found that increased left ventricular myocardial mass accompanied by a significant increase in blood pressure up to 90th percentile or more has occurred in childhood. Generally believed that the increase in left ventricular mass is the result of high blood pressure or high blood pressure. Only in recent years have a few authors found that an increase in left ventricular mass occurs before the increase in blood pressure in children. Hypertensive children with normotensive children or parents of high blood pressure, the quality of their left ventricular myocardial mass were higher than those without family history of hypertension. The researchers observed the relationship between hypertension and family history of hypertension and left ventricular myocardial mass, the results found that high-risk children with high blood pressure and family history of left ventricular myocardial mass higher than high-risk children without high blood pressure family history , Suggesting that in addition to increased blood pressure may be the cause of increased left ventricular myocardial mass, and the increase in left ventricular mass may still be the cause of hypertension, which may be inherent in the presence of left ventricular myocardium easily increased quality factor or Can not exclude the presence of abnormal ventricular myocytes.