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目的:分析出生缺陷发生的种类、相关因素及干预措施,为早期发现缺陷儿,提高产前诊断技术提供参考。方法:采用流行病学前瞻性研究方法,对2003～2007年围产儿出生缺陷情况进行分析。结果:17 767例围产儿中有出生缺陷儿97例,出生缺陷发生率为5.46‰,其中男婴59例,出生缺陷发生率为3.32‰,女婴36例,出生缺陷发生率为2.03‰,性别不明2例。出生缺陷前5位是唇腭裂、多指并指、外耳畸形、先心、马蹄内翻足。结论:应加强优生优育宣传力度,做好婚前保健、产前检查和产前筛查,减少出生缺陷,提高人口素质。
Objective: To analyze the types of birth defects, related factors and interventions for the early detection of defects in children, improve prenatal diagnosis techniques provide a reference. Methods: Epidemiological prospective study was used to analyze the incidence of perinatal birth defects from 2003 to 2007. Results: There were 97 cases of birth defects in 17 767 perinatal infants, the incidence of birth defects was 5.46 ‰, of which 59 were male infants, the incidence of birth defects was 3.32 ‰, 36 were female infants, the incidence of birth defects was 2.03 ‰, 2 cases of unknown gender. The first five birth defects are cleft lip and palate, multi-finger and refers to the outer ear deformity, heart, clubfoot. Conclusions: The prenatal and postnatal care, antenatal care and prenatal screening should be strengthened in order to reduce the birth defects and improve the population quality.