论文部分内容阅读
医生提醒,葡萄柚不能与某些药物同食。由于葡萄柚能抑制药物在体内降解,这可能引起药物剂量过量的潜在危险。首次证明葡萄柚能抑制药物降解的科研人员指出,能与葡萄柚发生作用的药物数量正在迅速增加。加拿大劳森健康研究所的科研小组称,能与葡萄柚产生副作用的药物数量由2008年的17种增加到2012的43种。这些药物中包括一系列降血压、抗癌和降胆固醇他汀类等药物以及器官移植后降低排斥反应的药物。在葡萄柚果实中含有一种天然呋喃香豆素,是阻止体内药物降解的主要物质,这意味着药物与葡萄柚
Doctors advise grapefruit can not be the same with some drugs. Since grapefruit can inhibit the degradation of the drug in the body, this may cause a potential danger of overdosage of the drug. Researchers who first demonstrated that grapefruit can inhibit drug degradation say the number of drugs that can work with grapefruit is rapidly increasing. According to a research team at Lawson Health Canada, the number of drugs that can cause side effects with grapefruit increased from 17 in 2008 to 43 in 2012. These include a range of drugs that lower blood pressure, anti-cancer and cholesterol-lowering statins, and drugs that reduce rejection after organ transplantation. Containing a natural furanocoumarin in grapefruit fruit is the main substance that stops the drug from degrading in the body, which means that the drug is mixed with grapefruit