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吡噻硫酮(Oltipraz)是一种新的高效抗血吸虫药物。本文旨在比较其与吡喹酮对血吸虫病的疗效,并进行了不同剂量的治疗试验。在加蓬的埃及血吸虫病和刚果的血吸虫病流行区,对5～14岁的学生作尿(过滤法)和粪便(MIFC法)检查,每例检查2次。165例血吸虫卵阳性者中,男性68例,女性97例,分两批随机分组观察,结果作卡方分析。第1批吡喹酮的治疗剂量均为2×30mg/kg,而吡噻硫酮组的治疗剂量分1×25mg/kg及
Oltipraz is a new and highly effective anti-schistosome drug. This article aims to compare its efficacy with praziquantel on schistosomiasis and to conduct different doses of treatment trials. In the areas of schistosomiasis in Egypt and schistosomiasis in the Congo in Gabon, urinary (Filtration) and fecal (MIFC) tests were performed on students aged 5-14 years with two examinations per case. 165 cases of schistosome egg-positive, 68 males and 97 females, divided into two batches were randomly divided into observations, the results for the chi-square analysis. The first batch of praziquantel treatment dose were 2 × 30mg / kg, and oltipraz group treatment dose of 1 × 25mg / kg and