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应用物质如何进入细胞的知识来制造杀死不需要的细胞的毒素。 三月份Minnesota大学的一个研究小组试验了一个新的大胆的白血病治疗法。一般给化疗后复发几次的白血病人都施行骨髓移植,但是由于供体骨髓可能含有能在白血病人中引起移植物抗宿主病的严重并发症的细胞,因而这些科学家将供体的骨髓预先以一种免疫毒素处理,这种处理是把一种极强的毒物挂到只识别能引起移植物抗宿主病的供体骨髓细胞的单克隆抗体上。此大学的John Kersey说,这个试验“标志着使用更有选择性的试剂,去除掉不需要的细胞的新纪元的开始”。
Knowledge of how the substance enters the cell creates toxins that kill unwanted cells. A team from Minnesota University in March tested a new bold leukemia treatment. Bone marrow transplants are generally administered to leukemia patients who relapse several times after chemotherapy. However, since the donor bone marrow may contain cells that can cause serious complications of graft versus host disease in leukemia patients, these scientists preliminarily An immunotoxin treatment that involves hooking a powerful poison to a monoclonal antibody that recognizes only donor bone marrow cells that cause graft-versus-host disease. John Kersey of the university said the trial “marks the beginning of a new era of using more selective reagents to get rid of unwanted cells.”