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目的探讨抗菌药物与抑胃酸分泌药物联合使用对消化性溃疡的临床治疗效果。方法 87例消化性溃疡患者,将其随机分为治疗组44例、对照组43例。治疗组给予奥美拉唑、左氧氟沙星、甲硝唑三种药物联合治疗的方法 ,对照组采用甲硝唑、左氧氟沙星、雷尼替丁三种药物联合治疗的方法。观察对比两组治疗效果。结果治疗组经联合治疗后总有效率为93.18%,对照组治疗的总有效率为74.42%,差异具有统计学意义(P<0.05);治疗组治疗后与治疗前临床症状评分比较差异有统计学意义(P<0.05)。结论采用甲硝唑、阿莫西林及奥美拉唑三种药物联合治疗消化性溃疡,可以显著提高临床疗效,促进溃疡的愈合,具有重要的临床应用和推广价值。
Objective To investigate the clinical efficacy of antibacterials and gastric acid-secreting drugs in the treatment of peptic ulcer. Methods A total of 87 patients with peptic ulcer were randomly divided into treatment group (44 cases) and control group (43 cases). The treatment group was given omeprazole, levofloxacin, metronidazole combined treatment of three drugs, the control group with metronidazole, levofloxacin, ranitidine three drugs combined treatment. Observed and compared the treatment effect of two groups. Results The total effective rate was 93.18% in the treatment group and 74.42% in the control group, the difference was statistically significant (P <0.05). There was statistical difference between the treatment group and the pre-treatment clinical symptom score Significance (P <0.05). Conclusion The combination of metronidazole, amoxicillin and omeprazole in the treatment of peptic ulcer can significantly improve the clinical curative effect and promote the healing of ulcer, which has important clinical application and promotion value.