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目的探讨自身免疫性溶血性贫血(AHIA)患者成分输血的临床疗效。方法对15例输注洗涤红细胞的AHIA患者(A组)和15例输注红细胞悬液的AHIA患者(B组)的临床资料进行回顾性对比分析。结果 A、B两组患者输血24h后,血红蛋白(Hb)、红细胞(RBC)数量和血细胞比容(Hct)均升高;同组内输血前后比较,差异均有统计学意义;两组间输血前后差异均无统计学意义。A组中5例患者输注洗涤红细胞联合血浆置换治疗AHIA,临床症状明显改善。结论输注洗涤红细胞与红细胞悬液治疗AHIA,其临床效果差异无统计学意义;输注洗涤红细胞联合血浆置换治疗AHIA效果显著。
Objective To investigate the clinical efficacy of blood transfusion in patients with autoimmune hemolytic anemia (AHIA). Methods The clinical data of 15 AHAH patients (Group A) infused with washed red blood cells and 15 AHAH patients (Group B) infused with red blood cells were retrospectively analyzed. Results The numbers of hemoglobin (Hb), erythrocytes (RBC) and hematocrit (Hct) in group A and group B were all increased after transfused for 24 hours. The blood transfusion levels in the same group were significantly different between before and after transfusion Before and after the difference was not statistically significant. In group A, 5 patients were infused with washed erythrocytes combined with plasma exchange to treat AHIA, and the clinical symptoms were significantly improved. Conclusions Infusion washing of erythrocyte and erythrocyte suspension in the treatment of AHIA has no significant difference in clinical effect; infusion of washed erythrocytes combined with plasma exchange for the treatment of AHIA has a significant effect.