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尽管对儿童白血病治疗目标已从缓解或延长缓解转到治愈上来,但现在仍不能定出一个治愈的客观标准。对此,作者检查了参加8种整体治疗方案之一的639例中已停药的278例儿童急性淋巴细胞白血病人治疗停止后的结果。停止治疗的指针为:(1) 完全缓解2.5年;(2)血液学完全缓解至少2.5年和髓外位置(如中枢神经系统或睾丸)复发而成功治疗至少1
Although the goal of treatment for childhood leukemia has shifted from relief or prolongation of relief to cure, an objective standard of cure can not be established. To this end, the authors examined the results of the cessation of treatment in 278 children with acute lymphoblastic leukemia who discontinued treatment in 639 patients enrolled in one of eight overall treatment regimens. Stop the treatment of the indicators: (1) complete remission 2.5 years; (2) hematology complete remission of at least 2.5 years and extramedullary position (such as the central nervous system or testicular) and the successful treatment of at least 1