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花白蜡树(Fraxinus ornus)属于木犀榄科植物,在保加利亚分布很广,传统医学中用其茎皮治疗炎症、关节炎和痢疾。文中比较研究了在体内、外实验中,花白蜡树茎皮乙醇提取物(TE)和马粟树皮甙(EN)对急性小鼠炎症反应的作用,并评价了TE和EN对小鼠血清补体活化经典途径(CP)和旁路途径(AP)的抑制作用。TE制备:取干燥的花白蜡树茎皮粉末以96％煮沸乙醇(3×360ml)提取3次,收集3次提取液,减压浓缩,得TE,该提取物经RP-HPLC分析,含EN40.0％,马粟树皮素2.35％,秦皮甙7.83％和秦皮素0.42％,EN标准品购自美国Aldrich化学公司。
Fraxinus ornus belongs to the family Arachniaceae and is widely distributed in Bulgaria. Traditional medicine uses its bark to treat inflammation, arthritis and dysentery. In this paper, we compared the effects of ethanol extract (TE) of E. purpurea bark and E. mutans (EN) on the inflammatory response of acute mice in vivo and in vitro, and evaluated the serum of TE and EN against mice. Complement activation activates the classical pathway (CP) and the alternative pathway (AP). TE preparation: The dried ash tree bark powder was extracted with 96% boiling ethanol (3×360 ml) three times, and the extract was collected three times and concentrated under reduced pressure to obtain TE. The extract was analyzed by RP-HPLC and contained EN40. 0%, Ma Suparin, 2.35%, Qinpi Coriander, 7.83%, and corterol, 0.42%, EN standard products were purchased from American Aldrich Chemical Company.