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前列腺素可在身体各部分产生,前列腺素一旦产生,很快即被灭活,除极少数例子外,多数在肺循环中破坏。前列腺素的形成: 前列腺素对心血管的作用:PGE_1和PGA_1是血管扩张剂,使血压降低,PGF_(2a)是血管收缩剂,使血压升高。对心血管系统的其他作用则相仿。环前列腺素(Prostacycline)(PGI_2):环
Prostaglandins can be produced in various parts of the body. Once prostaglandins are produced, they are quickly inactivated and, with a few exceptions, most are destroyed in the pulmonary circulation. Prostaglandin Formation: The Role of Prostaglandins in Cardiovascular Function PGE_1 and PGA_1 are vasodilators that lower blood pressure. PGF_ (2a) is a vasoconstrictor that increases blood pressure. Other effects on the cardiovascular system are similar. Prostacycline (PGI_2): Loop